N-Phthaloyl-glycine-hydroxamic acid as serum iron chelator in rats
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چکیده
منابع مشابه
N-phthaloyl-glycine-hydroxamic acid as serum iron chelator in rats.
The aim of this study was to investigate the activity of N-phthaloyl-glycine-hydroxamic acid (Phth-Gly-HA) as a new iron chelator in vivo to be used in iron overload diseases. After intraperitoneal application of Phth-Gly-HA to male rats (1 mg kg(-1) body mass) once a day for seven days, iron serum level decreased by 21%, whereas the iron value dropped by 32% in female rats (1.5 mg kg(-1) body ...
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The title co-crystal [systematic name: 3-(1,3-dioxoisoindolin-2-yl)propanoic acid-1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione (1/1)], C(8)H(10)N(4)O(2)·C(11)H(9)NO(4), is the combination of 1:1 adduct of N-phthaloyl-β-alanine with caffeine. The phthalimide and purine rings in the N-phthaloyl-β-alanine and caffeine mol-ecules are essentially planar, with r.m.s. deviations of the fitted atoms of 0...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2008
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-008-0010-7